Recurrent Pineoblastoma Responsive to Chemotherapy

نویسنده

  • P Kulshrestha
چکیده

Pineoblastomas are malignant embryonal tumours that are classified as suprasellar primitive neuroectodermal tumours. Incidence of pineoblastoma is approximately 0.1% to 0.3% of histogically verified primary malignant brain tumours. This case report concerns a 19-year-old male with a mass lesion in an area posterior to third ventricle, which was diagnosed as pineoblastoma. He achieved complete response after postoperative radiotherapy and chemotherapy. Disease recurred after 8 months in the form of drop metastasis at the level of C2-C4 in the spinal cord. He achieved complete response again following salvage chemotherapy. This report is submitted in view of rarity of this disease and its good response to chemotherapy after recurrence.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Treatment of a Pineoblastoma in a 51-year-old patient

Malignant pineal tumors are rare entities in adult patients, comprising less than 1% of primary central nervous system neoplasms. Herein, we report a 51-years-old patient with pineoblastoma with clinical manifestation, follow up MRI, treatment receive and the response to chemotherapy treatment. Adjuvant chemotherapy with cisplatin, etoposide and cyclophosphamide followed by radiotherapy has als...

متن کامل

Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with antineoplastons A10 and AS2-1.

Primitive neuroectodermal tumors (PNETs) are usually successfully treated with craniospinal radiation and chemotherapy; however, difficulties with standard treatment can be encountered in very young children, in adult patients at high risk of complication from standard treatment, and in patients with recurrent tumors. Thirteen children, either with recurrent disease or high risk, were treated i...

متن کامل

High-dose chemotherapy with autologous stem cell rescue for children with recurrent malignant brain tumors.

BACKGROUND High-dose chemotherapy (HDCT) with autologous stem cell rescue (ASCR) has been reported to be effective in treating children with recurrent central nervous system (CNS) malignancies. METHODS To evaluate the efficacy and toxicities of HDCT and ASCR, the medical records of 27 children with recurrent CNS malignancies who received such therapy at St. Jude Children's Research Hospital b...

متن کامل

High-Dose Chemotherapy with Autologous Hematopoietic Stem-Cell Rescue for Pediatric Brain Tumor Patients: A Single Institution Experience from UCLA

Background. Dose-dependent response makes certain pediatric brain tumors appropriate targets for high-dose chemotherapy with autologous hematopoietic stem-cell rescue (HDCT-AHSCR). Methods. The clinical outcomes and toxicities were analyzed retrospectively for 18 consecutive patients ≤19 y/o treated with HDCT-AHSCR at UCLA (1999-2009). Results. Patients' median age was 2.3 years. Fourteen had p...

متن کامل

Tackling a Recurrent Pinealoblastoma

Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimodality approach, surgery followed with radiation and chemotherapy. In view of aggressive nature few centr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006